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Considering that ALA could effectively stabilize hepatic Fe 2+ expression (Figure 1), and depress both levels of ferroptotic (Figure 2) and pro-apoptotic signaling (Figure 6), dietary supplementation with ALA may thus serve as a useful and practical way to prevent, or further counteract the CSD-induced liver injury and metabolic deficiency

Mejhert, N

The musculoskeletal side effects include muscle pain, muscle weakness, cramps and swelling in extremities including hands, arms, ankles, feet and/or lower legs

The basic strategy is to obtain a reagent focusing its activity prevalently around the cells expressing CD38, which enables avidity-induced blocking of CD47 on the same cells, in this way avoiding unwanted off-tumor effects

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